Comparative Study of Antioxidant, Antidiabetic, Cytotoxic Potentials, and Phytochemicals of Fenugreek (Trigonella foenum-graecum) and Ginger (Zingiber officinale)

Trigonella foenum-graecum and Zingiber officinale are used as traditional medicinal plants for the treatment of infectious inflammatory diseases. However, a comparative analysis bioactivities T. Z. lack some necessary information therapeutic purposes. This study was designed to evaluate biochemical characterizations biological efficacy antioxidant, antidiabetic, antiamnesic, cytotoxic agents. Antioxidant activity determined by DPPH free radical scavenging assay. Antidiabetic potentials were evaluated glycation, alpha-amylase, acetylcholinesterase inhibition assays. We performed characterization through analyses high-performance liquid chromatography (HPLC) FTIR (Fourier transform infrared spectroscopy). Results revealed that total phenolic contents (TPCs) (g GAE/100 g) 5.74 ± 0.81 g 6.15 0.06 g, respectively, flavonoid (TFCs) varied from 1.51 0.58 CE/100 17.54 0.58. extract 50.27% 88.82%, respectively. Antiglycation showed maximum at 16–29% 96%. Alpha-amylase alpha-glucosidase ranged 9.43–24.95 10.52–27.89 54.97%, All test samples potential 0.37–46.88%. HPLC presence quercetin, gallic acid, caffeic vanillic syringic cumeric while benzoic chlorogenic p.Coumaric ferulic cinnamic acid. aldehydes, ketones, aromatic compounds, amines, carbonyl groups in foenum-graecum, alcohol, alkane, alkene, ketone, amine, ether bioactives present methanolic officinale. It concluded higher effects.